Science behind Phew

Most Rx(prescription) constipation medicines are laxatives which can cause side-effects for long-term use. Often times, it doesn’t even work.

Traditional Eastern Medicine has a very different approach when it comes to constipation.

Constipation can occur when:

1. Excessive – There is excessive heat in the body, especially in the large intestine. Too much heat consumes the body fluid, which affects the stools in the bowel, which ultimately prevent from moving freely. The stools are dry or hard, and you may show other symptoms such as bad breath, dry mouth, dark urine, bloated stomach.⁽¹⁾
2. Deficient – there is an urge to go to the bathroom, although your stool is normal or wet you have to push really hard to release the stools. You may have cold limbs, a dislike for cold temperature, frequent belching, gas-retention (cannot let out the gas), bloated stomach.⁽¹⁾⁽²⁾

Although it seems simple, constipation comes with mixed reasons.
Phew is the only Traditional Eastern Medicine-based formula that is engineered to not only target multiple causes of constipation but it also tremendously enhances the functionality of your gut and promote healthier gut. Phew is an all-natural, constipation relief, and it is safe for long-term use.

 

It's piling up inside you if you don't get rid of it.

This is why bowel movement is critical. Phew specializes in enhancing bowel movement in a 2 different levels. 

 

 

The List of Herbs For Constipation Relief

Radix Angelica, Rhizoma Rhei, Hemp Seed, and Peach Seed will work on the excessive root causes.^(1)(2)(3)

Methionine in Radix Angelica enhances the contractile activity of the intestine ⁽⁴⁾. The right amount of Tryptophan and Arginine in Radix Angelica helps constipation caused by lack of Tryptophan and Arginine, which can lead to low serotonin can cause constipation. In Traditional Eastern Medicine, Radix angelica moistens the intestines and unblocks the bowels, expels abscess by tonify the blood, and regulating the body cycle. Also, it plays an immunostimulatory role in mitogen-stimulated murine lymphocytes in vitro. Angelan, a purified polysaccharide component of Radix Angelica thought to improve immune function, increases the expression of cytokines in splenocytes as Angelan enhances the production of interleukin-6 (IL-6) and interferon-γ(IFN-γ) of activated macrophages, helper T cells, and natural killer cells ⁽⁵⁾ to fight off any potential inflammatory possibility that could happen from constipated for a long time. 

Studies for Rhein⁽⁶⁾, Emodin⁽⁷⁾ in Rhizoma Rhei works as a very effective natural laxative that helps you go. Also, a strong antioxidant Catechine helps with constipation. Please remember, at Modern Herbs, we are all about the “Entourage effect” design to formulate to create synergy with all the herbs.

In Traditional Eastern Medicine, Rhizoma Rhei goes to the Large intestine meridian that brings the Qi(Energy) downward and also drains heat and purges accumulation of leftovers, and promotes urination and bowel movement.

We all know hemp seed is very popular for constipation. Its fatty oil in hemp seeds stimulates the intestinal mucus, increases secretion, reduces the absorption of water in the large intestine, and accelerates bowel movement ⁽⁸⁾. In Eastern Medicine, Hemp seeds go to the large intestine meridian that brings the Qi (Energy) downward, nourish, moisten, and lubricate the intestine, clear heat, and promote healing of sores. The peach seed also goes to the large intestine meridian not only moistening the intestines but also breaking blood stasis and invigorating blood circulation, unblocking the bowels and draining abscesses.⁽¹⁾

Magnolia bark, White Peony Root, Apricot Seed, Bitter Orange will work on the deficient root cause.^(1)(2)(3)

Varies studies show that Magnolia bark has many properties that treat-gastro-intestinal disorders, such as Salicifoline ⁽⁹⁾, Magnolol, Honokiol ⁽¹⁰⁾. Which works as a strong antioxidant and anti-inflammatory agent that help with chronic constipation due to lack of bowel movement. ⁽¹¹⁾ which are the same as the deficient case of constipation in Eastern Medicine. Also Magnolia is an aromatic herb that dispels dampness and goes to the large intestine meridian. Promotes and resolves the middle section of body stagnation (such as indigestion, belching, gas-retention, bloated stomach), bring the Qi (Energy) downward, and prevent Qi uprising. Remember, you are pushing out your Qi as you push out the junk. Simple concept, right?

White peony root has strong nature germicidal agent that kills harmful germs in our intestine, which works as an anti-inflammatory effect and oleic acid in white peony root reduces inflammation that is ready happened. And white peony root goes to spleen (spleen fights invading germs in the blood) meridian that nourishes the blood and regulates our body cycle and also relieves abdominal pain due to gas-retention, frequent belching.

Apricot seed and bitter orange go to large intestine meridians and it promotes the movement of qi, reduces distention and pressure (bloating, belching, gas-retention) softens the hardening, and removes stagnated food.

Medicated Leaven is a neutral herb that not only balances all herbs from excessive and deficient acting herbs (entourage effect!) but also goes to stomach meridian that helps digestion and harmonizes digestive track⁽¹⁾

 

Our Goal

Phew is your ultimate constipation one-stop-solution.

It’s the only thing that makes you relief a sign of "phew" in your daily lives.

Phew's proprietary formulation is based on Traditional Eastern Medicine.  Our team of doctors is dedicated to developing smart supplements that are helpful, valuable, and effective in maintaining your daily wellness.

 

 100% Natural | Vegan | No Chemicals | No Preservatives | No Sugar

Phew - When the moment comes.

 

References:

1. Nam Hee, Cho, Bong ha Ryu A study on constipation  Korean J. Orienta. Int. Med. 2000:2(1):169-180

2. Jae Hyun Kim, Yong Seok Park, Jihong Lee, Gyu Tae Chang Recent trends in Clinical Research of Herbal Medicine Treatment for Pediatric Constipation – Focused on Chinese Randomized Controlled Trials- Pediatr Korean Med. November, 2020:34(4):59-76

3. Jihong Lee, Sun Haeng Lee, Gyu Tae Chang Trends in Clinical Research of Herbal Medicine Treatment for Functional Gastrointestinal Disorders in Children Pediatr Korean Med, May, 2021;35(3):67-88

4. Eun Kyung Choe, Jung Sun Moon, Kyu Joo Park Methionine Enhances the Contractile Activity of Human Colon Circular Smooth Muscle In Vitro., J Korean Med Sci. 2012 Jul; 27(7): 777–783.

5. Han SB, Kim YH, Lee CW, Park SM, Lee HY, Ahn KS, Kim IH, Kim HM .Characteristic immunostimulation Immunopharmacology Volume 40, Issue 1, July 1998, P39-48

6. Li-Li Sun, Hong-bo Jiang, Bo-Yu Liu, Wen-Dong Li, Ai-Lin Du, Xiao Qiu Luo, Xiao Qing Li Effects of rhein on intestinal transmission, colonic electromyography and expression of aquaporin-3 by colonic epithelium cells in constipated mice Int J Clin Exp Pathol. 2018; 11(2): 614–623.

7. Yan-Fang Zheng, Chun-Fang Liu, Wen-Fang Lai, Qing Xiang, Zuan-Fang Li, Hui Wang, Na Lin The laxative effect of emodin is attributable to increased aquaporin 3 expression in the colon of mice and HT-29 cells Fitoterapia 2014 Jul;96:25-32.

8. Xiao-Fang Lu, Meng-Di Jia, Sheng-Sheng Zhang, Lu Qing Zhao Effects of Hemp seed soft capsule on colonic ion transport in rats World J Gastroenterol. 2017 Nov 14; 23(42): 7563–7571.

9. Kefalew A., Asfaw Z., Kelbessa E. Ethnobotany of medicinal plants in Ada’a District, East Shewa Zone of Oromia regional state, Ethiopia. J. Ethnobiol. Ethnomed. 2015;11:1–28

10. Wei-Wei Zhang, Yan Li, Wue-Qing Wang, Feng Tian, hong Cao, Min-Wei Wang, Qi-Shi Sun Effects of magnolol and honokiol derived from traditional Chinese herbal remedies on gastrointestinal movement World J Gastroenterol. 2005 Jul 28; 11(28): 4414–4418.

11. Bruno J. C silva, Ana M.L seca, Maria do Carmo Barreto , Diana C. G . A. Pinto Recent Breakthroughs in the Antioxidant and Anti-Inflammatory Effects of Morella and Myrica Species Int J Mol Sci. 2015 Aug; 16(8): 17160–17180.